Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2
نویسندگان
چکیده
منابع مشابه
Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2
Filamins are long, flexible, multi-domain proteins composed of an N-terminal actin-binding domain (ABD) followed by multiple immunoglobulin-like repeats (IgFLN). They function to organize and maintain the actin cytoskeleton, to provide scaffolds for signaling components, and to act as mechanical force sensors. In this study, we used transcript sequencing and homology modeling to characterize th...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0022428